I-Microalgae ingenye yezinhlobo ezindala kakhulu eMhlabeni, uhlobo lolwelwe oluncane olungakhula emanzini ahlanzekile nasolwandle ngezinga elimangalisayo lokuzalana. Ingasebenzisa kahle ukukhanya kanye ne-carbon dioxide ekwenzeni i-photosynthesis noma isebenzise imithombo ye-organic carbon elula ukukhula kwe-heterotrophic, futhi ihlanganise imisoco ehlukahlukene efana namaprotheni, ushukela, namafutha ngokusebenzisa i-metabolic metabolism.

Ngakho-ke, ama-microalgae athathwa njengamaseli e-chassis afanelekile okufeza ukukhiqizwa kwebhayoloji eluhlaza futhi esimeme, futhi asetshenziswe kabanzi emikhakheni ehlukahlukene efana nokudla, imikhiqizo yezempilo, imithi, izimonyo, i-biofuels, kanye ne-bioplastics.

Muva nje, inkampani yasekhaya ye-microalgae synthetic biology, i-Protoga Biotech, imemezele ukuthi iphrotheni yayo entsha ye-microalgae isiphumelele ngempumelelo isigaba sokukhiqiza umshayeli, ngamandla okukhiqiza aphezulu angama-600 kilograms amaprotheni ngosuku. Umkhiqizo wokuqala osuselwe kuphrotheni ye-microalgae emisha, ubisi lwesitshalo se-microalgae, nawo usuphumelele uhlolo lokuhlola futhi kulindeleke ukuthi wethulwe futhi udayiswe ekupheleni kwalo nyaka.

Ethatha leli thuba, u-Shenghui waxoxa noDkt. Li Yanqun, unjiniyela omkhulu wokuthuthukiswa kwezicelo ku-protoga Biotechnology. Wethula ku-Shenghui imininingwane yokuhlolwa komshayeli okuphumelelayo kwe-microalgae protein kanye namathemba okuthuthukiswa emkhakheni wamaprotheni ezitshalo. U-Li Yanqun uneminyaka engaphezu kwengu-40 yokuhlangenwe nakho komsebenzi wesayensi nezobuchwepheshe emkhakheni wokudla okukhulu, obambe iqhaza kakhulu ocwaningweni nasekuthuthukisweni kwezicelo ze-microalgae biotechnology kanye ne-biotechnology yokudla. Uthole iziqu ze-PhD ku-Fermentation Engineering e-Jiangnan University. Ngaphambi kokujoyina i-protoga Biology, usebenze njengoprofesa eSikoleni SeSayensi Yokudla Nobuchwepheshe, e-Guangdong Ocean University.

“Njengoba igama lenkampani lisho, i-protoga Biotechnology idinga ukusungula izinto ezintsha kusukela ekuqaleni futhi ibe nekhono lokukhula kusukela ekuqaleni. I-protoga imele umoya oyinhloko wenkampani, okuwukuzibophezela kwethu ekusunguleni izinto ezintsha emthonjeni nasekuthuthukisweni kobuchwepheshe obusha kanye nemikhiqizo. Imfundo iwukuhlakulela futhi ikhule, futhi ubuchwepheshe nemiqondo yokuqamba kabusha emthonjeni kudingeka ithuthuke ibe imboni entsha, imodi entsha yokusetshenziswa, ngisho nefomethi entsha yezomnotho. Sivule indlela entsha yokukhiqiza imikhiqizo enenani eliphezulu sisebenzisa ulwelwe oluncane, okuyisithasiselo esibalulekile ekukhiqizweni nasekuhlinzekweni kwezinsiza zokudla, ngokuhambisana nombono wamanje okhuthazwayo wokudla okukhulu, sibe sithuthukisa nezindaba zemvelo.” U-Li Yanqun utshele uShenghui.

Ubuchwepheshe busuka eNyuvesi yaseTsinghua, bugxile ekukhuthazeni amaprotheni ezitshalo ze-microalgae
I-protoga Biotechnology yinkampani ye-biotechnology eyasungulwa ngo-2021, igxile ekuthuthukisweni nasekucutshungulweni komkhiqizo wobuchwepheshe be-microalgae. Ubuchwepheshe bayo buthathwe cishe eminyakeni engama-30 yokuqoqwa kocwaningo elabhorethri ye-microalgae yaseTsinghua University. Imininingwane yomphakathi ikhombisa ukuthi selokhu yasungulwa, inkampani ikhulise ama-yuan angaphezu kwezigidi eziyi-100 ekuxhaseni ngezimali futhi yandisa isikali sayo.

Njengamanje, isisungule ilabhorethri yokucwaninga nokuthuthukiswa kwezobuchwepheshe ye-synthetic biology e-Shenzhen, isizinda sokuhlola umshayeli e-Zhuhai, imboni yokukhiqiza e-Qingdao, kanye nesikhungo sokumaketha samazwe ngamazwe e-Beijing, esihlanganisa ukuthuthukiswa komkhiqizo, ukuhlolwa komshayeli, ukukhiqiza, kanye izinqubo zokuhweba.

Ngokukhethekile, ilabhorethri yokucwaninga nokuthuthukiswa kobuchwepheshe yebhayoloji yokwenziwa e-Shenzhen igxile kakhulu ocwaningweni oluyisisekelo futhi inochungechunge lwezobuchwepheshe oluphelele olusuka kubunjiniyela bamaseli ayisisekelo, ukwakhiwa kwendlela ye-metabolic, ubuchwepheshe bokuhlola ubunzima kuya ekuthuthukisweni komkhiqizo; Inesisekelo somshayeli wamamitha-skwele angama-3000 eZhuhai futhi isifakwe ekukhiqizeni umshayeli. Isibopho sawo esiyinhloko ukukhuphula ukuvutshelwa nokutshalwa kolwelwe noma izinhlobo zebhaktheriya ezithuthukiswe ilabhorethri ye-R&D ngesilinganiso sokulinga, nokuqhubeka nokucubungula i-biomass ekhiqizwa ukuvutshelwa ibe yimikhiqizo; Imboni ye-Qingdao iwumugqa wokukhiqiza wezimboni obhekele ukukhiqizwa kwemikhiqizo emikhulu.

Ngokusekelwe kulezi zinkundla zobuchwepheshe nezindawo zokukhiqiza, sisebenzisa izindlela zezimboni ukutshala ulwelwe oluncane futhi sikhiqize izinto ezingavuthiwe ezisekelwe kulwelwe oluncane oluncane kanye nemikhiqizo eyinqwaba, okuhlanganisa amaprotheni ama-microalgae, i-levastaxanthin, ama-microalgae exosomes, uwoyela we-DHA algal, nama-polysaccharides e-algae enqunu. Phakathi kwazo, uwoyela we-DHA algal kanye nama-polysaccharides e-algae anqunu asungulwe ukudayiswa, kuyilapho iphrotheni ye-microalgae ingumkhiqizo wethu omusha emthonjeni kanye nephrojekthi eyinhloko yokukhuthaza nokukala ukukhiqizwa. Eqinisweni, isikhundla esiyinhloko samaprotheni ama-microalgal singabonakala futhi egameni lesiNgisi le-metazoa, elingaqondwa njengesifinyezo se-"protein of microalga"

Iphrotheni ye-Microalgae iphumelele ngempumelelo ukuhlolwa kokuhlola, futhi kulindeleke ukuthi ubisi olusekelwe esitshalweni se-microalgae luzokwethulwa ekupheleni konyaka.
“Amaprotheni ayisakhamzimba esibalulekile esingahlukaniswa abe amaprotheni ezilwane kanye namaprotheni ezitshalo. Kodwa-ke, kusenezinkinga ngokutholakala kwamaprotheni anganele futhi angalingani emhlabeni wonke. Isizathu salokhu ukuthi ukukhiqizwa kwamaprotheni ikakhulukazi kuncike ezilwaneni, ngekhono eliphansi lokuguqula kanye nezindleko eziphezulu. Ngokushintsha kwemikhuba yokudla kanye nemibono yokusetshenziswa, ukubaluleka kwamaprotheni ezitshalo kuya ngokuya kugqama. Sikholelwa ukuthi amaprotheni ezitshalo, njengeprotheyini entsha ye-microalgae esiyithuthukisile, inamandla amakhulu okuthuthukisa ukutholakala kwamaprotheni, ”kusho uLi Yanqun.

Uphinde wethula ukuthi uma kuqhathaniswa nabanye, iphrotheni yesitshalo se-microalgae yenkampani inezinzuzo eziningi ekusebenzeni kahle kokukhiqiza, ukufana, ukuzinza, ukuvikelwa kwemvelo, kanye nenani lokudla okunempilo. Okokuqala, iphrotheni yethu ye-microalgal empeleni ifana “nephrotheni yokuvutshelwa”, okuyiphrotheni yezitshalo ekhiqizwa kusetshenziswa ubuchwepheshe bokuvutshelwa. Ngokuphambene, inqubo yokukhiqiza le phrotheni evutshiwe iyashesha, futhi inqubo yokuvutshelwa ingenzeka unyaka wonke ngaphandle kokuthintwa yinkathi; Ngokuphathelene nokulawula nokuvumelana, inqubo yokuvutshelwa yenziwa endaweni elawulwayo, engaqinisekisa ikhwalithi nokuvumelana komkhiqizo. Ngesikhathi esifanayo, ukubikezela nokulawulwa kwenqubo yokuvutshelwa kuphakeme, okunganciphisa ithonya lesimo sezulu nezinye izici zangaphandle; Mayelana nokuphepha, inqubo yokukhiqiza le phrotheni evutshiwe ingakwazi ukulawula kangcono ukungcola namagciwane, ithuthukise ukuphepha kokudla, futhi yandise impilo yeshalofu yomkhiqizo ngobuchwepheshe bokuvutshelwa; Iphrotheni yethu yezitshalo ezivutshiwe nayo inezinzuzo zemvelo. Inqubo yokuvutshelwa inganciphisa ukusetshenziswa kwemithombo yemvelo efana nomhlabathi namanzi, inciphise ukusetshenziswa kukamanyolo nezibulala-zinambuzane ekukhiqizeni kwezolimo, futhi iphinde yehlise i-carbon footprint kanye nokukhishwa kwegesi ebamba ukushisa.

Ngaphezu kwalokho, inani lokudla okunomsoco we-microalgae plant protein nalo licebile kakhulu. Ukwakheka kwayo kwe-amino acid kunengqondo futhi kuhambisana nephethini yokwakheka kwe-amino acid etuswe i-World Health Organization kunaleyo yezitshalo ezinkulu ezifana nerayisi, ukolweni, ummbila, nobhontshisi wesoya. Ngaphezu kwalokho, amaprotheni esitshalo se-microalgae aqukethe kuphela inani elincane lamafutha, ikakhulukazi amafutha angenayo i-unsaturated, futhi ayinayo i-cholesterol, ezuzisa kakhulu ibhalansi yokudla okunempilo komzimba. Ngakolunye uhlangothi, amaprotheni esitshalo se-microalgae aqukethe nezinye izakhi, okuhlanganisa i-carotenoids, amavithamini, amaminerali asekelwe ku-bio, njalonjalo. " Kusho uLi Yanqun ngokuzethemba.

U-Shenghui ufunde ukuthi isu lenkampani lokuthuthukisa amaprotheni ama-microalgae lihlukaniswe izingxenye ezimbili. Ngakolunye uhlangothi, ukuthuthukisa izinto ezintsha zamaprotheni e-microalgae ukuhlinzeka ngezinto zokusetshenziswa zezinkampani ezifana nokudla, izimonyo, noma ama-biological agents; Ngakolunye uhlangothi, uchungechunge lwemikhiqizo ehlobene selusungulwe ngokusekelwe kuphrotheni ye-microalgae emisha, eyenza i-matrix yemikhiqizo yamaprotheni e-microalgae. Umkhiqizo wokuqala ubisi lwesitshalo se-microalgae.

Kuyafaneleka ukusho ukuthi iphrotheni ye-microalgae yenkampani isanda kudlula isigaba sokukhiqiza umshayeli, enamandla okukhiqiza umshayeli angaba ngu-600 kg / ngosuku we-microalgae protein powder. Kulindeleke ukuthi yethulwe ungakapheli lo nyaka. Ukwengeza, iphrotheni yolwelwe oluncane iphinde yenziwa ukuhlelwa kwempahla yobuhlakani efanele futhi yafaka isicelo sochungechunge lwamalungelo obunikazi okusungulwa. U-Li Yanqun ukubeke kwacaca ukuthi ukuthuthukiswa kwamaprotheni kuyisu lesikhathi eside lenkampani, futhi i-microalgal protein iyisixhumanisi esibalulekile ekufezeni leli su. Ukuhlolwa kokuhlola okuyimpumelelo kwephrotheni yolwelwe oluncane kulokhu kuyingqophamlando ebalulekile ekufezeni isu lethu lesikhathi eside. Ukuqaliswa kwemikhiqizo emisha kuzofaka isandla ekuthuthukisweni okunempilo kwenkampani futhi kulethe ubungqabavu obunamandla ekusebenzeni kwayo okuqhubekayo; Emphakathini, lokhu ukuqaliswa komqondo womqondo omkhulu wokudla, okuqhubeka nokucebisa izinsiza zemakethe yokudla.

Ubisi lwezitshalo luyisigaba esikhulu sokudla okusekelwe ezitshalweni emakethe, okuhlanganisa ubisi lwe-soy, ubisi lwe-walnut, ubisi lwe-peanut, ubisi lwe-oat, ubisi lukakhukhunathi, nobisi lwe-almond. Ubisi lwesitshalo solwelwe oluncane lwe-protoga Biology luzoba isigaba esisha sobisi olusekelwe ezitshalweni, okulindeleke ukuthi lwethulwe futhi ludayiswe ekupheleni kwalo nyaka, futhi luzoba ubisi lokuqala emhlabeni oluhweba ngempela lwezitshalo zolwelwe oluncane.

Ubisi lwesoya lunokuqukethwe kwamaprotheni amaningi uma kuqhathaniswa, kodwa kunephunga likabhontshisi kanye nezici ezilwa nomsoco kubhontshisi wesoya, okungase kuphazamise ukusetshenziswa kwawo ngempumelelo emzimbeni. I-Oat iwumkhiqizo wokusanhlamvu onokuqukethwe kwamaprotheni aphansi, futhi ukudla inani elifanayo lamaprotheni kuzoholela kuma-carbohydrates amaningi. Ubisi lwezitshalo olunjengobisi lwe-alimondi, ubisi lukakhukhunathi, nobisi lwamakinati lunokuqukethwe uwoyela okuphezulu, futhi lungadla uwoyela owengeziwe lapho ludliwe. Uma kuqhathaniswa nale mikhiqizo, ubisi lwesitshalo se-microalgae lunamafutha aphansi kanye nokuqukethwe kwesitashi, okunokuqukethwe okuphezulu kwamaprotheni. Ubisi lwesitshalo se-Microalgae oluvela ezilwaneni zakudala lwenziwa nge-microalgae, equkethe i-lutein, i-carotenoid, namavithamini, futhi inomsoco ocebile. Esinye isici ukuthi Lolu bisi olusekelwe esitshalweni lukhiqizwa kusetshenziswa amangqamuzana e-algae futhi lugcina imisoco ephelele, kuhlanganise ne-fiber yokudla ecebile; Mayelana ne-flavour, ubisi lwe-protein esekelwe esitshalweni luvame ukuba nokunambitheka okuthile okutholakala ezitshalweni ngokwazo. I-microalgae yethu ekhethiwe inephunga elimnandi le-microalgal futhi ilawulwa ukuze yethule ukunambitheka okuhlukile ngobuchwepheshe bobunikazi. Ngikholelwa ukuthi ubisi olusekelwe esitshalweni se-microalgae, njengohlobo olusha lomkhiqizo, luzoqhuba futhi luholele ekuthuthukisweni kwemboni, ngaleyo ndlela lukhuthaze ukuthuthukiswa kwayo yonke imakethe yobisi esekelwe esitshalweni uLi Yanqun wachaza.

“Imakethe yamaprotheni ezitshalo ibhekene nethuba elihle lokuthuthuka”
Amaprotheni ezitshalo awuhlobo lwamaprotheni atholakala ezitshalweni, agayeka kalula futhi amuncwa umzimba womuntu. Ingenye yemithombo ebalulekile yamaprotheni okudla komuntu futhi, njengamaprotheni ezilwane, ingasekela imisebenzi ehlukahlukene yokuphila njengokukhula komuntu kanye nokunikezwa kwamandla. Kubantu abadla imifino, abantu abangezwani namaprotheni ezilwane, kanye nezinkolelo ezithile zenkolo kanye nezazi zemvelo, kunobungane nakakhulu ngisho nesidingo.

“Ngokombono wesidingo sabathengi, izindlela zokudla okunempilo, nokuphepha kokudla, siyakhula isidingo sabantu sokudla okusimeme kanye nezindawo zamaprotheni enyama. Ngikholelwa ukuthi ingxenye yamaprotheni ezitshalo ekudleni kwabantu izoqhubeka nokukhula, futhi ukwakheka okuhambisanayo kanye nokunikezwa kwezinto zokusetshenziswa zokudla kuzophinde kube nezinguquko eziphawulekayo. Ngamafuphi, isidingo samaprotheni ezitshalo sizoqhubeka sikhuphuka esikhathini esizayo, futhi imakethe yamaprotheni ezitshalo ingenisa ithuba elihle lentuthuko, "kusho uLi Yanqun.

Ngokombiko we-The Bussiness Research Company's 2024 Global Market Report on Plant Protein, usayizi wemakethe wamaprotheni ezitshalo ubukhula kakhulu eminyakeni yamuva nje. Usayizi wemakethe ngo-2024 uzokhula ufinyelele ku- $ 52.08 billion, futhi kulindeleke ukuthi usayizi wemakethe kulo mkhakha ukhuphuke ufinyelele ku- $ 107.28 billion ngo-2028, ngesilinganiso sokukhula saminyaka yonke esicishe sibe ngu-19.8%.

U-Li Yanqun uqhube wathi, “Eqinisweni, imboni yamaprotheni ezitshalo inomlando omude futhi ayiyona imboni esafufusa. Kule minyaka eyishumi edlule, njengoba yonke imakethe yamaphrotheni ezitshalo iba ngohlelo kanye nezimo zengqondo zabantu ezishintshayo, isiphinde yadonsa ukunakwa. Kulindeleke ukuthi izinga lokukhula kwezimakethe zomhlaba lifinyelele ku-20% eminyakeni eyi-10 ezayo.”

Kodwa-ke, ubuye waveza ukuthi nakuba imboni yamaprotheni ezitshalo okwamanje isesigabeni sokuthuthukiswa okusheshayo, kusenezinkinga eziningi okufanele zixazululwe futhi zithuthukiswe ohlelweni lokuthuthukiswa. Okokuqala, kunendaba yemikhuba yokudla. Kwamanye amaprotheni ezitshalo ezingezona ezendabuko, abathengi badinga ukuzijwayeza kancane kancane inqubo yokwamukela; Bese kuba nendaba yokunambitheka kwamaprotheni ezitshalo. Amaprotheni ezitshalo ngokwawo ane-flavour eyingqayizivele, edinga nenqubo yokwamukelwa nokuqashelwa. Ngesikhathi esifanayo, ukwelashwa okufanele ngokusebenzisa izindlela zobuchwepheshe kuyadingeka futhi esigabeni sokuqala; Ngaphezu kwalokho, kunezinkinga ngezindinganiso zokulawula, futhi okwamanje, amanye amaprotheni ezitshalo angase ahileleke ezindabeni ezifana nokuntuleka kwemithetho efanele okufanele ilandelwe.