PRPTOGA MICROALGAE CDMO IINKONZO

- Ithala leencwadi leMicroalgae

Unikezelo lweMbewu yeMicroalgae

▪ Ithala leencwadi iPROTOGA Microalgae ligcine phantse ikhulu leentsholongwane ezincinci, kuquka kodwa zingaphelelanga kwiHaematococcus Pluvialis, Chlorella sp., Dictyosphaerium sp., Scenedesmus sp. kunye ne-Synechocystis sp.. Zonke iimbewu ze-algae zihlanjululwa kwaye ziqinisekisiwe njenge-microalgae ethile enokusetyenziswa kuphando lwezenzululwazi.

Ukwahlulwa kweMicroalgae

▪ I-PROTOGA inokwahlula kwaye ihlambulule i-microalgae yendalo kumachibi, emilanjeni, kwimigxobhozo, enokuthi ihlolwe kwiingcinezelo ezahlukeneyo (ubushushu obuphezulu / obuphantsi, ubumnyama / ukukhanya kunye njl.). Abathengi bethu banokuba ngabanini be-microalgae ecociweyo kwaye ihlolwe kuphando, amalungelo abenzi, uphuhliso lwezorhwebo.

Ukuzalana ngokuguquguqukayo

▪ I-PROTOGA iseke inkqubo esebenzayo ye-ARTP ye-microalgae mutagenesis, ngakumbi efanelekileyo kwezinye iintlobo eziqhelekileyo. I-PROTOGA inokwakha inkqubo entsha ye-ARTP kunye nebhanki eguqukayo xa kufuneka i-microalgae ethile.

- Uzinzo

Xa kuthelekiswa neoli yeentlanzi kunye nokutya okusekelwe kwizilwanyana, i-microalgae izinzileyo kunye nendalo. I-Microalgae iya kuba zizisombululo ezithembisayo kwingxaki ekhoyo kwishishini lokutya, ukulima kunye nokufudumala kwehlabathi.

I-PROTOGA izibophelele ekuphuhliseni itekhnoloji entsha ye-microalgal ekhawulezisa uhlaziyo lweshishini le-microalgae, inceda ekudambiseni ingxaki yokutya yehlabathi, ukunqongophala kwamandla kunye nongcoliseko lokusingqongileyo. Sikholelwa ukuba i-microalgae inokukhuthaza ihlabathi elitsha ukuba abantu baphile ngendlela enempilo kunye neluhlaza.

-Imveliso elungiselelweyo

I-Microalgae Fermentation & Post-Processing

i.PROTOGA yakhe ngaphezu kwe-100 square metres yeplanti ye-C-level ngokuhambelana ne-ISO Class7 kunye ne-GMP, kunye negumbi lenkcubeko yobushushu kunye nokufuma kunye nommandla ococekileyo ngokuhambelana neemfuno zelayisensi yokuvelisa ukutya, enokuthi yenziwe ngokuhambelana nomthengi. iimfuno.
ii.Sixhotyiswe ngoluhlu oluchanekileyo oluchanekileyo lwe-fermenters oluzenzekelayo oluyi-5L ukuya kwi-1000L, olugubungela isikali selebhu ukuya kwimveliso ye-pilot-scale.
iii.I-Post-processing ibandakanya ukuqokelelwa kweeseli, ukomisa, ukugaya ibhola kunye nokunye.
iv.Izixhobo zovavanyo kunye nezixhobo ezifana ne-HPLC kunye ne-GC ziqhuba uhlalutyo lwemveliso ye-biomass, i-carotenoids, i-fatty acids, i-organic carbon, i-nitrogen, i-phosphorus kunye nezinye izinto.

- Ibhayoloji yeMolekyuli

I-Microalgal Plasmid Bank
▪ I-Microalgal Plasmid Bank ibandakanya kodwa ingaphelelanga kwii-plasmids zoguqulo eziqhelekileyo. I-Plasmid Bank ibonelela ngeentlobo ngeentlobo zezityalo ezifanelekileyo nezisebenzayo kwizifundo ezahlukeneyo.

UPhuculo lwe-AI yolandelelwano lweGene
▪ I-PROTOGA iye yakha inkqubo yokuphucula imfuza ngokufunda kwe-AI. Umzekelo, inokwandisa i-ORF kwiimfuza zangaphandle, ibone ulandelelwano olukwinqanaba eliphezulu lokubonisa, incede ekujoliswe kuyo kwi-gene overexpress.

Ukugqithisa kakhulu kwiChlamydomonas reinhardtii
▪ I-PROTOGA's Chlamydomonas reinhardtii yenziwe nge-microalgal chassis ye-protein yangaphandle ebonisa ngokugqithisileyo i-HA, Strep okanye i-GFP. Ngokweemfuno zakho, iprotheni ekujoliswe kuyo inokubonakaliswa kwi-cytoplasm okanye i-chloroplast.

I-Gene Knockout kwiChlamydomonas reinhardtii
▪ Iqela lobuchwephesha bePROTOGA lakhe inkqubo yokuhlela iCrispr/cas9 kunye neCrispr/cas12a eChlamydomonas reinhardtii, kubandakanywa uyilo lwe-gRNA, itemplate yeDNA yomxhasi, indibano enzima kunye nezinye izinto, ezenza i-gene knockout kunye ne-site-directed mutagenesis.