I-Microalgae yenye yezona ntlobo zindala eMhlabeni, uhlobo lwe-algae encinci enokukhula kumanzi ahlambulukileyo kunye namanzi olwandle ngesantya esimangalisayo sokuzala. Inokusebenzisa ngokufanelekileyo ukukhanya kunye nekhabhon diokside kwiphotosynthesis okanye isebenzise imithombo elula yekhabhoni ephilayo ekukhuleni kwe-heterotrophic, kwaye idibanise izondlo ezahlukeneyo ezinje ngeeproteni, iswekile, kunye neoyile ngemetabolism yeselula.

Ke ngoko, i-microalgae ithathwa njengeeseli ze-chassis ezifanelekileyo zokuphumeza ukuveliswa kwebhayoloji eluhlaza kunye nozinzo, kwaye zisetyenziswe ngokubanzi kwiindawo ezahlukeneyo ezinjengokutya, iimveliso zempilo, amayeza, izithambiso, i-biofuels, kunye ne-bioplastics.

Kutshanje, inkampani yasekhaya ye-microalgae synthetic biology, i-Protoga Biotech, ibhengeze ukuba iprotein yayo entsha ye-microalgae iphumelele ngempumelelo inqanaba lokuvelisa ulingo, ngomthamo omkhulu wemveliso we-600 yeekhilogram zeprotheyini ngosuku. Imveliso yokuqala esekelwe kwiprotheyini entsha ye-microalgae, ubisi lwesityalo se-microalgae, nayo iphumelele uvavanyo lokulinga kwaye kulindeleke ukuba iqaliswe kwaye ithengiswe ekupheleni kwalo nyaka.

Ukuthatha eli thuba, uShenghui udlan’ indlebe noGqr. Li Yanqun, injineli eyintloko yophuhliso lwesicelo kwi-protoga Biotechnology. Wazisa ku-Shenghui iinkcukacha zovavanyo oluyimpumelelo lweprotheyini ye-microalgae kunye nethemba lophuhliso kwintsimi yeprotheni yezityalo. U-Li Yanqun uneminyaka engaphezu kwama-40 yamava omsebenzi wenzululwazi kunye nobuchwepheshe kwintsimi yokutya okukhulu, ngokukodwa ukuzibandakanya kuphando kunye nophuhliso lwesicelo se-microalgae biotechnology kunye ne-biotechnology yokutya. Wathweswa isidanga sePhD kubuNjineli beFermentation kwiYunivesithi yaseJiangnan. Phambi kokujoyina iProtoga Biology, ebesebenza njengonjingalwazi kwiSikolo seSayensi yoKutya kunye neTekhnoloji, kwiYunivesithi yaseGuangdong Ocean.

“Njengoko igama lenkampani lisitsho, iprotoga Biotechnology kufuneka ivelise izinto ezintsha ukusuka ekuqaleni kwaye ibe nokukwazi ukukhula ukusuka ekuqaleni. Iprotoga imele umoya ongundoqo wenkampani, oyisibophelelo sethu ekuveliseni izinto ezintsha kumthombo kunye nophuhliso loqobo lwetekhnoloji kunye neemveliso. Imfundo yeyokulima kwaye ikhule, kwaye itekhnoloji kunye neengqikelelo zokuqamba izinto ezintsha kwindawo kufuneka ziphuhliselwe kushishino olutsha, indlela entsha yokusetyenziswa, kunye nefomathi entsha yezoqoqosho. Siye savula indlela entsha yokuvelisa iimveliso zexabiso eliphezulu kusetyenziswa i-microalgae, esongezelelo esibalulekileyo kwimveliso kunye nokubonelela ngemithombo yokutya, ngokuhambelana nombono okhoyo ngoku wokutya okukhulu, ngelixa uphucula imiba yokusingqongileyo. " U-Li Yanqun uxelele uShenghui.

Ubuchwephesha buvela kwiYunivesithi yaseTsinghua, ngokugxila ekukhuthazeni iiprotheni zezityalo ze-microalgae
Iprotoga Biotechnology yinkampani yebiotechnology esekwe ngo-2021, igxile kuphuhliso kunye nokusetyenzwa kwemveliso yobuchwepheshe be-algae. Itekhnoloji yayo ithathwe phantse kwiminyaka eyi-30 yokuqokelela uphando kwilebhu ye-microalgae yeYunivesithi yaseTsinghua. Ulwazi loluntu lubonisa ukuba ukusukela oko yasekwa, inkampani inyuse ngaphezulu kwe-100 yezigidi zeeyuan ekuxhaseni ngemali kwaye yandise isikali sayo.

Okwangoku, iseke iteknoloji yophando kunye nelebhu yophuhliso yebhayoloji yokwenziwa e-Shenzhen, isiseko sovavanyo e-Zhuhai, umzi-mveliso wemveliso eQingdao, kunye neziko lentengiso yamazwe ngamazwe eBeijing, eligubungela uphuhliso lwemveliso, uvavanyo lokulinga, imveliso, kunye iinkqubo zorhwebo.

Ngokukodwa, uphando lwetekhnoloji kunye nelebhu yophuhliso yebhayoloji yokwenziwa e-Shenzhen igxile ikakhulu kuphando olusisiseko kwaye inekhonkco lobugcisa elipheleleyo elisuka kubunjineli obusisiseko beeseli, ukwakhiwa kwendlela ye-metabolic, itekhnoloji yokuhlola uxinzelelo ukuya kuphuhliso lwemveliso; Inesiseko sokulinga se-3000 square metres e-Zhuhai kwaye ifakwe kwimveliso yokulinga. Olona xanduva lwayo kukunyusa ukuvutshelwa kunye nokulinywa kwe-algae okanye iintlobo zebhaktheriya eziphuhliswe ilebhu ye-R&D kwisikali sokulinga, kwaye iqhubekisele phambili i-biomass eveliswa ngokuvutshelwa kwiimveliso; Umzi-mveliso we-Qingdao ngumgca wemveliso wemizi-mveliso ojongene nokuveliswa kweemveliso ezinkulu.

Ngokusekelwe kula maqonga ezobuchwepheshe kunye nezixhobo zokuvelisa, sisebenzisa iindlela zoshishino ukuhlakulela i-microalgae kunye nokuvelisa izinto ezahlukeneyo ze-microalgae ezisekelwe kwizinto eziluhlaza kunye neemveliso ezininzi, kuquka iprotheni ye-microalgae, i-levastaxanthin, i-microalgae exosomes, i-oyile ye-algal ye-DHA, kunye ne-polysaccharides ye-algae ehamba ze. Phakathi kwabo, ioli ye-algal ye-DHA kunye ne-polysaccharides ye-algae enqunu iye yasungulwa ukuze ithengiswe, ngelixa iprotheni ye-microalgae iyimveliso yethu entsha kumthombo kunye neprojekthi ephambili yokukhuthaza kunye nokulinganisa imveliso. Ngapha koko, indawo ephambili ye-microalgal proteins inokubonwa nakwigama lesiNgesi le-metazoa, elinokuqondwa njengesifinyezo se "protein ye-microalga"

Iprotein ye-Microalgae iphumelele uvavanyo lokulinga, kwaye kulindeleke ukuba ubisi olusekelwe kwisityalo se-microalgae luya kusungulwa ekupheleni konyaka.
“Iprotein sisondlo esibalulekileyo esinokwahlulwa sibe yiprotein yezilwanyana kunye neprotein yezityalo. Nangona kunjalo, kusekho imiba yokungonelanga kunye nokubonelela ngeprotheyini engalinganiyo kwihlabathi jikelele. Isizathu emva koku kukuba imveliso yeprotheyini ixhomekeke kakhulu kwizilwanyana, ngokuguqulwa okuphantsi kokuguqulwa kunye neendleko eziphezulu. Ngotshintsho kwimikhwa yokutya kunye neengcamango zokusetyenziswa, ukubaluleka kweprotheni yezityalo kuya kuphawuleka ngakumbi. Sikholelwa ukuba iprotheni yezityalo, ezifana neprotein entsha ye-microalgae esiyiphuhlileyo, inamandla amakhulu okuphucula ukunikezelwa kweeprotheyini, "utshilo uLi Yanqun.

Waphinda wazisa ukuba xa kuthelekiswa nabanye, iprotheni yesityalo se-microalgae yenkampani ineenzuzo ezininzi ekusebenzeni kakuhle kwemveliso, ukufana, ukuzinza, ukukhuselwa kwendalo kunye nexabiso lesondlo. Okokuqala, iprotein yethu ye-microalgal eneneni ifana “neprotein yokubila”, eyiprotein yezityalo eveliswa kusetyenziswa itekhnoloji yokubila. Ngokwahlukileyo koko, inkqubo yokuvelisa le proteni enegwele ikhawuleza, kwaye inkqubo yokuvundisa inokwenzeka unyaka wonke ngaphandle kokuchatshazelwa lixesha lonyaka; Ngokumalunga nokulawulwa kunye nokuhambelana, inkqubo yokuvutshelwa iqhutyelwa kwindawo elawulwayo, enokuqinisekisa umgangatho kunye nokuhambelana kwemveliso. Ngelo xesha, ukuqikelelwa kunye nokulawulwa kwenkqubo yokuvuthwa kuphezulu, enokunciphisa impembelelo yemozulu kunye nezinye izinto zangaphandle; Ngokuphathelele ukhuseleko, inkqubo yokuvelisa le proteni enegwele inokulawula ngcono ungcoliseko kunye ne-pathogens, iphucule ukhuseleko lokutya, kwaye yandise ubomi beshelufu yemveliso ngokusebenzisa ubuchwepheshe bokubilisa; Iprotheyini yethu yesityalo esivundisiweyo nayo ineenzuzo zokusingqongileyo. Inkqubo yokuvutshelwa inokunciphisa ukusetyenziswa kwemithombo yendalo efana nomhlaba kunye namanzi, ukunciphisa ukusetyenziswa kwezichumisi kunye nezibulala-zinambuzane kwimveliso yezolimo, kunye nokunciphisa i-carbon footprint kunye ne-greenhouse gas emissions.

Ukongeza, ixabiso lesondlo seprotein yesityalo se-microalgae sityebile kakhulu. Ukwakheka kwayo kwe-amino acid kusengqiqweni ngakumbi kwaye ihambelana nepateni yokwakheka kwe-amino acid enconyelwa nguMbutho wezeMpilo weHlabathi kuneso sezityalo ezikhulu ezifana nerayisi, ingqolowa, umbona, kunye neembotyi zesoya. Ukongezelela, iprotheni yesityalo se-microalgae iqulethe kuphela inani elincinci leoli, ngokukodwa ioli e-unsaturated, kwaye ayinayo i-cholesterol, enenzuzo ngakumbi kwibhalansi yesondlo somzimba. Ngakolunye uhlangothi, iprotheni yesityalo se-microalgae iqulethe ezinye izondlo, kuquka i-carotenoids, iivithamini, iiminerali ezisekelwe kwi-bio, njalo njalo. " Utshilo uLi Yanqun ngokuzithemba.

U-Shenghui wafunda ukuba isicwangciso sophuhliso lwenkampani yeprotheni ye-microalgae yahlulwe ibe yimiba emibini. Kwelinye icala, ukuphuhlisa izinto ezintsha zeprotheyini yealgae ukubonelela ngemathiriyeli ekrwada kwiinkampani ezinjengokutya, izinto zokuthambisa, okanye iiarhente zebhayoloji; Ngakolunye uhlangothi, uluhlu lweemveliso ezinxulumene nazo ziqaliswe ngokusekelwe kwiprotheni ye-microalgae entsha, eyenza i-matrix yeemveliso zeprotheni ye-microalgae. Imveliso yokuqala yi-microalgae plant milk.

Kuyafaneleka ukukhankanya ukuba iprotheni ye-microalgae yenkampani isanda kudlula inqanaba lokuvelisa umqhubi, kunye nomthamo wokuvelisa umqhubi malunga ne-600 kg / ngosuku lwe-microalgae protein powder. Kulindeleke ukuba isungulwe kulo nyaka. Ukongeza, i-microalgae protein iye yafumana iprotein efanelekileyo yobukrelekrele kwaye yafaka isicelo kuthotho lwamalungelo awodwa omenzi wechiza. U-Li Yanqun wachaza ngokucacileyo ukuba uphuhliso lweprotheni sisicwangciso sexesha elide lenkampani, kwaye iprotheni ye-microalgal iyikhonkco ebalulekileyo ekufezekiseni esi sicwangciso. Uvavanyo oluyimpumelelo lweprotein yolwelwe oluncinci ngeli xesha linyathelo elibalulekileyo ekuphumezeni isicwangciso sethu sexesha elide. Ukuphunyezwa kweemveliso ezintsha kuya kuba negalelo kuphuhliso olusempilweni lwenkampani kwaye izise amandla okuqina ekusebenzeni kwayo okuqhubekayo; Kuluntu, oku kukuphunyezwa kwengqikelelo yengqikelelo yokutya okukhulu, ngakumbi ukutyebisa izixhobo zentengiso yokutya.

Ubisi lwezityalo luluhlu olukhulu lokutya okusekelwe kwizityalo kwiimarike, kubandakanya ubisi lwesoya, ubisi lwe-walnut, ubisi lwe-peanut, ubisi lwe-oat, ubisi lwekakhukhunathi, kunye nobisi lwe-almond. Ubisi olusekwe kwisityalo se-microalgae ye-protoga Biology luya kuba luhlobo olutsha lobisi olusekelwe kwizityalo, ekulindeleke ukuba lusungulwe kwaye luthengiswe ekupheleni kwalo nyaka, kwaye luza kuba lolokuqala ubisi lwezityalo olusekwe kwisityalo solwelwe oluncinci.

Ubisi lwesoya lunomthamo weprotheyini ephezulu, kodwa kukho ivumba lembotyi kunye nezinto ezichasene nesondlo kwiimbotyi zesoya, ezinokuchaphazela ukusetyenziswa kwayo okusebenzayo emzimbeni. I-Oat yimveliso yeenkozo kunye nomxholo weprotheyini ephantsi, kwaye ukutya umlinganiselo ofanayo weprotheni kuya kubangela i-carbohydrates eninzi. Ubisi lwezityalo olufana nobisi lwe-almond, ubisi lwekhokhonathi, kunye nobisi lwe-peanut lunomthamo ophezulu we-oyile, kwaye lunokutya ioli eninzi xa lutyiwe. Xa kuthelekiswa nezi mveliso, ubisi lwesityalo se-microalgae luneoli ephantsi kunye nomxholo wesitashi, kunye nomxholo ophezulu weprotheyini. Ubisi lwesityalo se-Microalgae olusuka kwizinto zamandulo lwenziwe kwi-microalgae, equkethe i-lutein, i-carotenoids, kunye neevithamini, kwaye inexabiso elicebileyo lesondlo. Olunye uphawu kukuba Olu bisi olusekwe kwisityalo luveliswa kusetyenziswa iiseli ze-algae kwaye lugcina izondlo ezipheleleyo, kuquka i-fiber ecebileyo yokutya; Ngokubhekiselele kwincasa, ubisi lweprotein esekelwe kwizityalo luhlala lunencasa ethile evela kwizityalo ngokwazo. I-microalgae yethu ekhethiweyo inevumba elincinci le-microalgal kwaye ilawulwa ukuba ibonise iincasa ezahlukeneyo ngeteknoloji yobunini. Ndiyakholelwa ukuba ubisi olusekwe kwisityalo se-microalgae, njengohlobo olutsha lwemveliso, ngokuqinisekileyo luya kuqhuba kwaye lukhokele uphuhliso loshishino, ngaloo ndlela lukhuthaza uphuhliso lwemarike yobisi olusekelwe kwizityalo uLi Yanqun wachaza.

"Imarike yeprotheyini yezityalo ijongene nethuba elihle lophuhliso"
Iprotein yezityalo luhlobo lweprotheyini ephuma kwizityalo, etyiswa lula kwaye ifunnwe ngumzimba womntu. Ngomnye wemithombo ebalulekileyo yeprotheni yokutya komntu kwaye, njengeprotheni yezilwanyana, inokuxhasa imisebenzi eyahlukeneyo yobomi efana nokukhula komntu kunye nokunikezelwa kwamandla. Kubantu abatya imifuno, abantu abaneeprotheyini zezilwanyana, kunye neenkolelo ezithile zonqulo kunye neengcali zokusingqongileyo, zinobuhlobo ngakumbi kwaye ziyimfuneko.

“Ngokwembono yemfuno yabathengi, indlela yokutya okunempilo, kunye nokhuseleko lokutya, imfuno yabantu yokutya okuzinzileyo kunye neendawo zeprotheyini yenyama iyanda. Ndiyakholelwa ukuba umlinganiselo weprotheyini yezityalo ekutyeni kwabantu uya kuqhubeka nokukhula, kwaye isakhiwo esihambelanayo kunye nokunikezelwa kwezinto eziluhlaza zokutya nazo ziya kutshintsha kakhulu. Ngamafutshane, imfuno yeprotheyini yezityalo iya kuqhubeka nokunyuka kwixesha elizayo, kwaye imarike yeprotheyini yezityalo ingenisa ithuba elihle lophuhliso, "utshilo uLi Yanqun.

Ngokutsho kweNkampani yoPhando lwezoShishino lweNgxelo yeMarike yeHlabathi ka-2024 kwiProtein yeSityalo, ubungakanani bentengiso yeprotein yezityalo buye bakhula kakhulu kwiminyaka yakutshanje. Ubungakanani bemarike ngo-2024 buya kukhula bufikelele kwi-52.08 yeebhiliyoni zeedola, kwaye kulindeleke ukuba ubungakanani bemarike kule ndawo bunyuke iye kuthi ga kwi-107.28 yeebhiliyoni zeedola ngo-2028, kunye nesantya sokukhula sonyaka esimalunga ne-19.8%.

U-Li Yanqun waphinda wathi, "Enyanisweni, ishishini leprotheyini yezityalo linembali ende kwaye ayiloshishini elikhulayo. Kule minyaka ilishumi idlulileyo, yonke imarike yeprotheyini yezityalo iye yacwangciswa ngakumbi kunye nezimo zengqondo zabantu eziguqukayo, iphinde yatsala umdla. Kulindeleke ukuba izinga lokukhula kwemarike yehlabathi lisondele kuma-20% kule minyaka ili-10 izayo.”

Nangona kunjalo, ukhankanye ukuba nangona imboni yeprotheyini yezityalo okwangoku ikhula ngokukhawuleza, kusekho iingxaki ezininzi eziza kusonjululwa kwaye ziphuculwe kwinkqubo yophuhliso. Okokuqala, kukho umba wemikhwa yokusebenzisa. Kwezinye iiprotheni zezityalo ezingezizo ezemveli, abathengi kufuneka baziqhelanise ngokuthe ngcembe nenkqubo yokwamkelwa; Emva koko kukho umba wencasa yeeprotheni zezityalo. Iiprotheni zezityalo ngokwazo zinencasa ekhethekileyo, ekwafuna inkqubo yokwamkelwa kunye nokuqatshelwa. Ngelo xesha, unyango olufanelekileyo ngeendlela zobugcisa luyimfuneko kwinqanaba lokuqala; Ukongezelela, kukho imiba enemigangatho yokulawula, kwaye ngoku, ezinye iiprotheni zezityalo zinokubandakanyeka kwimiba efana nokungabikho kwemimiselo efanelekileyo yokulandela.