I-Astaxanthin Synthesis kwiChlamydomonas Reinhardtii

I-PROTOGA isandula ukubhengeza ukuba idibanise ngempumelelo i-astaxanthin yendalo kwi-Chlamydomonas Reinhardtii ngokusebenzisa i-Microalgae ye-Genetic Modification Platform, kwaye ngoku iphuhlisa ipropathi yobukrelekrele obunxulumeneyo kunye nophando lokusetyenzwa phantsi komlambo. Kuxelwa ukuba esi sisizukulwana sesibini seeseli zobunjineli ezibekwe kumbhobho we-astaxanthin kwaye ziya kuqhubeka nokuphindaphinda. Isizukulwana sokuqala seeseli zobunjineli singene kwinqanaba lovavanyo lokulinga. I-synthesis ye-astaxanthin kwi-Chlamydomonas Reinhardtii yokuvelisa imveliso iya kuba phezulu kwiindleko, imveliso kunye nomgangatho kune-Haematococcus Pluvialis.

I-Astaxanthin yindalo kunye ne-synthetic xanthophyll kunye ne-nonprovitamin A carotenoid, ene-antioxidant enokubakho, i-anti-inflammatory kunye ne-antineoplastic imisebenzi. Umsebenzi wayo we-antioxidant ngamaxesha e-6000 ye-vitamin C kunye namaxesha e-550 ye-vitamin E. I-Astaxanthin inomsebenzi ogqwesileyo kwi-immune regulation, ukugcinwa kwenkqubo ye-cardiovascular system, impilo yamehlo kunye nengqondo, amandla esikhumba, ukulwa nokuguga kunye nezinye izicelo. I-Astaxanthin ihlala isetyenziswa kwiimveliso zokhathalelo lwempilo, iimveliso zesondlo esinesondlo esinesiphumo sokhathalelo lwempilo kwaye yongezwa kwizithambiso ezinempembelelo ye-antioxidant.

Imakethi yehlabathi ye-astaxanthin kulindeleke ukuba ifikelele kwi-2.55 yeebhiliyoni zeedola ngo-2025 ngokutsho kweGrand View Research. Okwangoku, umsebenzi we-astaxanthin ofunyenwe kwi-chemical synthesis kunye ne-Phaffia rhodozyma iphantsi kakhulu kunaleyo isuka kwi-levo-astaxanthin yendalo evela kwi-microalgae ngenxa yomsebenzi wayo we-optical optical. Yonke i-levo-astaxanthin yendalo kwimarike ivela kwi-Haematococcus Pluvialis. Nangona kunjalo, ngenxa yokukhula okucothayo, umjikelo wenkcubeko omde kwaye kulula ukuchatshazelwa yimiba yokusingqongileyo, amandla okuvelisa i-Haematococcus Pluvialis alinganiselwe.

Njengomthombo omtsha weemveliso zendalo kunye neseli ye-chassis yebhayoloji yokwenziwa, i-microalgae inenethiwekhi ye-metabolic entsonkothileyo kunye neenzuzo ze-biosynthesis. I-Chlamydomonas Reinhardtii yipateni ye-chassis, eyaziwa ngokuba yi "yeast eluhlaza". I-PROTOGA ibambe itekhnoloji yokuhlela yemfuza ephucukileyo ye-microalgae kunye netekhnoloji yokubila kwe-microalgae esezantsi. Ngelo xesha, i-PROTOGA iphuhlisa iteknoloji ye-photoautotrophic .Xa iteknoloji yokuzala ikhulile kwaye ingasetyenziselwa ukuveliswa kwesikali, iya kuphakamisa i-synthesis ye-synthesis yokuguqula i-CO2 kwiimveliso ezisekelwe kwi-bio.