Kweli xesha likhawulezayo nelinoxinzelelo oluphezulu, impilo ibe yenye yezona zinto zixabisekileyo kuthi. Ngokuqhubela phambili kwetekhnoloji kunye nokujula kophando lwezondlo, abantu baya beqonda ngakumbi ukuba ukongeza kukutya okunokulinganisela kunye nokuzilolonga okuphakathi, i-antioxidants idlala indima ebaluleke kakhulu ekugcineni impilo yomzimba kunye nokuchasana nomonakalo omkhulu wasimahla. Namhlanje, masiqalise uhambo lokuphonononga kunye ukuze sifunde malunga nenkqubo ephindaphindwayo yee-antioxidants ukusuka kwizipho zamandulo zendalo ukuya kwi-synthesis yesayensi yale mihla, kunye nendlela abaye baba ngamaqabane abalulekileyo kukhathalelo lwempilo lwemihla ngemihla.

1, Intshayelelo kwiiAntioxidants: Isipho esivela kwiNdalo
I-Antioxidants, ngamagama alula, luhlobo lwento enokuthintela okanye icothise inkqubo ye-oxidation. I-oxidation ikhona yonke indawo kubomi bethu bemihla ngemihla, ukusuka kwizikhonkwane zentsimbi ezigqwalayo ukuya kukonakala kokutya, zonke ezi ziziphumo ze-oxidation. Emzimbeni womntu, impendulo ye-oxidation nayo iyimfuneko njengoko isisiseko sokuvelisa amandla. Nangona kunjalo, xa le mpendulo iphuma kulawulo kwaye ivelisa i-radicals yamahhala, iya konakalisa isakhiwo seseli, i-DNA kunye nomzimba wonke, isantya sokwaluphala, kwaye ibangele izifo ezahlukeneyo, ezifana nesifo senhliziyo, umhlaza kunye nomhlaza. isifo seswekile.

Ubulumko bendalo buxhomekeke kwinto yokuba sele ilungiselele umthombo ocebileyo we-antioxidants kuthi. Kwakudala, abantu bafumanisa ukutya okuninzi kwendalo okuneziphumo ze-antioxidant ngokuqwalasela kunye nokuziqhelanisa, njengeziqhamo ze-citrus ezityebileyo kwi-vitamin C, i-carrots ecebile kwi-beta carotene, kunye ne-blueberries ecebile kwi-anthocyanins. Amacandelo e-antioxidant koku kutya anokuthi anciphise ii-radicals zasimahla emzimbeni, akhusele iiseli emonakalweni, kwaye abe sisixhobo sendalo sabantu sokuxhathisa izifo kunye nokugcina amandla olutsha.

2, Uphononongo lwezeNzululwazi: Ukutsiba ukusuka kuKutya ukuya kwizicatshulwa
Ngokunyuka kwe-biochemistry kunye nesondlo, izazinzulu ziye zaqala ukukhangela kwisakhiwo, indlela yokusebenza, kunye ne-bioavailability yezi zixhobo zendalo ze-antioxidant. Embindini wenkulungwane yama-20, kunye nenkqubela phambili yokwahlula kunye neteknoloji yokuhlanjululwa, abantu bakhupha ngempumelelo ii-antioxidants ezahlukeneyo kwizityalo, iziqhamo, kunye neenkozo, ezifana ne-vitamin E, i-vitamin C, i-selenium, i-carotenoids, kunye ne-polyphenols yezityalo ezahlukeneyo, kwaye bazisa ukuba imarike ngohlobo lwezongezelelo, inika ukhetho olutsha kwabo bangakwaziyo ukuhlangabezana neemfuno zabo ze-antioxidant ngokutya kwemihla ngemihla.

Ngeli xesha, ukusetyenziswa kwe-antioxidants akuzange kuphele kunyango lokutya okuqhelekileyo, kodwa kwangena kwintsimi yolawulo lwezempilo olusulungekileyo kunye nokuthintela izifo. Izazinzulu ziye zaqinisekisa iziphumo ezilungileyo zee-antioxidants ezithile ekunciphiseni umngcipheko wesifo senhliziyo, ukuphucula ukusebenza komzimba, kunye nokulibazisa ukuguga kwesikhumba ngovavanyo lweklinikhi, ukuqhubela phambili ukukhuthaza ukuchuma kwentengiso ye-antioxidant.

I-3, Ukufika kwexesha lokwenziwa: izisombululo ezichanekileyo nezisebenzayo ze-antioxidant
Nangona i-antioxidants yendalo ineenzuzo ezininzi, ukuzinza kwazo, i-bioavailability, kunye nokunciphisa umsebenzi phantsi kweemeko ezithile eziye zabangela ukuba izazinzulu zihlolisise iindlela ezintsha-zokwenziwa kwe-antioxidants. I-Synthetic Antioxidants, eyenziwe ngezinto zokulwa ne-antioxidant ezenziwe ngobuchule ngeendlela zeekhemikhali, zijolise ekoyiseni imida ethile ye-antioxidant yendalo kunye nokubonelela ngokhuseleko oluchanekileyo, olusebenzayo kunye noluzinzileyo lwe-antioxidant.

Phakathi kwabo, i-antioxidant ye-synthetic emele kakhulu iquka i-butyl hydroxyanisole (BHA), i-dibutyl hydroxytoluene (BHT), kwaye kutshanje ifumene ingqalelo efana ne-lipoic acid. Ezi khompawundi ziyilwe ngononophelo ukuba zikhuphe ngokufanelekileyo ii-radicals zasimahla, ngelixa zigcina uzinzo oluhle kunye nobomi obude beshelufu, zibenza bafanelekele ukusetyenzwa kokutya okwahlukeneyo, ukwenziwa kwamayeza, kunye nophuhliso lwemveliso yezempilo.

Kuyafaneleka ukuba uqaphele ukuba ukusetyenziswa kwe-antioxidants ye-synthetic ayikho ngaphandle kwengxabano. Uvavanyo lokhuseleko, ulawulo lwethamo, kunye nophando lwefuthe lexesha elide bezisoloko ziyingqwalasela yeenzululwazi. Ukuqinisekisa ukuba ama-antioxidants okwenziwa abonelela ngezibonelelo zempilo ngaphandle kokubangela iziphumo ezibi emzimbeni womntu yeyona nto iphambili kuphando lwesayensi.

I-4, amathemba ekamva: Izicwangciso zomntu zokulwa ne-antioxidant
Ngophuhliso olukhawulezayo lwe-genomics, i-metabolomics, kunye ne-bioinformatics, singena kwixesha leyeza elichanekileyo. Uphando lwexesha elizayo lwe-antioxidant kunye nophuhliso luya kuhlawulela ngakumbi ukungafani komntu ngamnye, kwaye ulungelelanise izicwangciso ze-antioxidant kumntu ngamnye ngovavanyo lwemfuza, uhlalutyo lwe-metabolic, kunye nezinye iindlela. Oku kuthetha ukuba i-antioxidants yexesha elizayo ayinakuba nje izongezo ezilula zezondlo, kodwa izicwangciso zongenelelo ezibanzi ezisekelwe kulwazi oluninzi olufana nemvelaphi yofuzo, indlela yokuphila, kunye nesimo sempilo.

Ukongeza, ukudityaniswa kwe-nanotechnology kunye ne-biotechnology kuya kuzisa utshintsho oluguqukayo kuphuhliso lwe-antioxidants. Ngetekhnoloji ye-nanocarrier, i-antioxidants inokungena ngokufanelekileyo ngakumbi kwi-membrane yeseli kwaye ifikelele kwizicubu ekujoliswe kuzo; I-Biotechnology inokudala iimolekyuli ezintsha ze-antioxidant ezinomsebenzi ophezulu kunye nokucacileyo, ivula isahluko esitsha ekusetyenzisweni kwee-antioxidants.