Astaxanthin Synthesis muChlamydomonas Reinhardtii

PROTOGA nguva pfupi yadarika yakazivisa kuti yakabudirira kugadzira astaxanthin yemusikirwo muChlamydomonas Reinhardtii kuburikidza neMicroalgae Genetic Modification Platform, uye ikozvino iri kugadzira hupfumi hwakabatana uye kudzika kwepasi kwekugadzirisa tsvagiridzo. Zvinonzi ichi ndicho chizvarwa chechipiri chemasero einjiniya akaiswa muastaxanthin pombi uye acharamba achidzokorora. Chizvarwa chekutanga chemasero einjiniya chapinda munhanho yekuyedza. Iyo synthesis yeastaxanthin muChlamydomonas Reinhardtii yekugadzirwa kwemaindasitiri ingave yepamusoro mumutengo, kugadzirwa uye mhando kupfuura iyo yeHaematococcus Pluvialis.

Astaxanthin ndeye yakasikwa uye yakagadzirwa xanthophyll uye nonprovitamin A carotenoid, ine inogona kuita antioxidant, anti-kuzvimba uye antineoplastic zviitiko. Its antioxidant activity is 6000 times that of vitamin C and 550 times that of vitamin E. Astaxanthin ine basa rakanakisisa mukugadzirisa zvirwere, cardiovascular system kuchengetedza, maziso uye hutano hwehuropi, simba reganda, anti-kukwegura uye mamwe maitiro. Astaxanthin inowanzo shandiswa muzvigadzirwa zvekuchengetedza hutano, zvigadzirwa zvekudya zvine hutano hwehutano uye zvinowedzerwa muzvizoro zvine antioxidant maitiro.

Musika wepasi rose weastaxanthin unotarisirwa kusvika pamadhora mazana maviri nemakumi mashanu emadhora panosvika 2025 maererano neGrand View Research. Parizvino, kuita kweastaxanthin kunowanikwa kubva kumakemikari synthesis uye Phaffia rhodozyma yakadzikira pane iyo kubva kune yakasikwa levo-astaxanthin inotorwa kubva kumicroalgae nekuda kwemaitiro ayo ekuona. Yese yakasikwa levo-astaxanthin pamusika inobva kuHaematococcus Pluvialis. Nekudaro, nekuda kwekukura kwayo kunonoka, kutenderera kwetsika refu uye nyore kukanganiswa nemamiriro ekunze, kugona kwekugadzira kweHaematococcus Pluvialis kushoma.

Sesosi nyowani yezvigadzirwa zvechisikigo uye chassis sero rekugadzira biology, microalgae ine yakanyanya kuoma metabolic network uye biosynthesis zvakanakira. Chlamydomonas Reinhardtii ndiyo pateni chassis, inozivikanwa se "girinhi mbiriso". PROTOGA inyanzvi yepamberi microalgae genetic editing tekinoroji uye yakadzika microalgae kuvirisa tekinoroji. Panguva imwecheteyo, PROTOGA iri kugadzira photoautotrophic technologies .Kana teknolojia yekuberekesa yakura uye inogona kushandiswa pachiyero-kugadzirwa, ichasimudza kushandiswa kwekugadzirisa kushandura CO2 kune bio-based products.