Astaxanthin Synthesis mu Chlamydomonas Reinhardtii

PROTOGA posachedwapa yalengeza kuti yapanga bwino astaxanthin yachilengedwe ku Chlamydomonas Reinhardtii kudzera pa Microalgae Genetic Modification Platform, ndipo tsopano ikupanga luntha logwirizana ndi kafukufuku wokonza zinthu zakumunsi. Akuti uwu ndi m'badwo wachiwiri wama cell a engineering omwe adayikidwa mu payipi ya astaxanthin ndipo apitiliza kubwereza. Mbadwo woyamba wa ma cell a mainjiniya walowa muyeso yoyeserera. Kaphatikizidwe ka astaxanthin ku Chlamydomonas Reinhardtii pakupanga mafakitale kungakhale kopambana mtengo, zokolola komanso mtundu kuposa wa Haematococcus Pluvialis.

Astaxanthin ndi chilengedwe komanso kupanga xanthophyll komanso nonprovitamin A carotenoid, yomwe imatha kukhala ndi antioxidant, anti-inflammatory and antineoplastic. Ntchito yake ya antioxidant ndi nthawi za 6000 za vitamini C ndi nthawi za 550 za vitamini E. Astaxanthin ali ndi ntchito yabwino kwambiri yoyendetsera chitetezo cha mthupi, kukonza dongosolo la mtima, thanzi la maso ndi ubongo, mphamvu ya khungu, anti-kukalamba ndi ntchito zina. Astaxanthin nthawi zambiri amagwiritsidwa ntchito pazinthu zachipatala, zakudya zopatsa thanzi zomwe zimakhala ndi thanzi komanso zimawonjezeredwa muzodzola zokhala ndi antioxidant effect.

Msika wapadziko lonse wa astaxanthin ukuyembekezeka kufika $2.55 biliyoni pofika 2025 malinga ndi Grand View Research. Pakadali pano, zochita za astaxanthin zomwe zimapezedwa kuchokera kumaphatikizidwe amankhwala ndi Phaffia rhodozyma ndizotsika kwambiri kuposa zalevo-astaxanthin yochokera ku microalgae chifukwa cha mawonekedwe ake owoneka bwino. Levo-astaxanthin yonse yachilengedwe pamsika imachokera ku Haematococcus Pluvialis. Komabe, chifukwa cha kukula kwake pang'onopang'ono, kuzungulira kwa chikhalidwe chachitali komanso kosavuta kukhudzidwa ndi zinthu zachilengedwe, mphamvu yopangira Haematococcus Pluvialis ndi yochepa.

Monga gwero latsopano lazinthu zachilengedwe komanso cell chassis ya biosynthetic biology, microalgae imakhala ndi maukonde ovuta kwambiri a metabolic ndi maubwino a biosynthesis. Chlamydomonas Reinhardtii ndi mtundu wa chassis, wotchedwa "green yeast". PROTOGA adadziwa ukadaulo wapamwamba wosintha ma genetic wa microalgae komanso ukadaulo wakutsika wa microalgae fermentation. Panthawi imodzimodziyo, PROTOGA ikupanga matekinoloje a photoautotrophic .Tekinoloje yobereketsa ikakhwima ndipo ingagwiritsidwe ntchito pakupanga sikelo, idzakweza kaphatikizidwe kamene kamasintha CO2 kuzinthu zopangira zamoyo.