Astaxanthin Synthesis na Chlamydomonas Reinhardtii

PROTOGA na nso nso a mara ọkwa na ọ gara nke ọma synthesized eke astaxanthin na Chlamydomonas Reinhardtii site Microalgae Genetic Modification Platform, na ugbu a na-emepe emepe ihe metụtara ọgụgụ isi na nyocha nhazi ala. A na-akọ na nke a bụ ọgbọ nke abụọ nke mkpụrụ ndụ injinia nke edobere na pipeline astaxanthin ma ga-aga n'ihu na-emegharị. Ọgbọ mbụ nke mkpụrụ ndụ injinia abanyela n'ọkwa ule nnwale. Ngwakọta nke astaxanthin na Chlamydomonas Reinhardtii maka mmepụta ụlọ ọrụ ga-adị elu na ọnụ ahịa, nrụpụta na ịdị mma karịa nke Haematococcus Pluvialis.

Astaxanthin bụ eke na sịntetik xanthophyll na nonprovitamin A carotenoid, nwere ike antioxidant, mgbochi mkpali na antineoplastic omume. Ọrụ antioxidant ya bụ 6000 ugboro nke vitamin C na 550 ugboro nke vitamin E. Astaxanthin nwere arụmọrụ magburu onwe ya na nhazi nke usoro ahụ ji alụso ọrịa ọgụ, nhazi usoro obi obi, ahụike anya na ụbụrụ, ike anụ ahụ, mgbochi ịka nká na ngwa ndị ọzọ. A na-ejikarị Astaxanthin na ngwaahịa nlekọta ahụike, ngwaahịa nri nri nwere mmetụta nlekọta ahụike yana gbakwunyere na ịchọ mma nwere mmetụta antioxidant.

Ahịa astaxanthin zuru ụwa ọnụ na-atụ anya iru $ 2.55 ijeri site na 2025 dị ka Nnyocha Nleba anya. Ka ọ dị ugbu a, ọrụ nke astaxanthin enwetara site na njikọ kemịkalụ na Phafia rhodozyma dị ala karịa nke sitere na levo-astaxanthin eke sitere na microalgae n'ihi ọrụ nhazi ya. Levo-astaxanthin eke sitere n'ahịa sitere na Haematococcus Pluvialis. Otú ọ dị, n'ihi na ọ na-eto ngwa ngwa, ogologo omenala okirikiri na mfe na-emetụta gburugburu ebe obibi, ike mmepụta nke Haematococcus Pluvialis nwere oke.

Dị ka isi iyi ọhụrụ nke ngwaahịa eke na chassis cell nke usoro ihe ọmụmụ ihe, microalgae nwere netwọkụ metabolic dị mgbagwoju anya na uru biosynthesis. Chlamydomonas Reinhardtii bụ chassis ụkpụrụ, nke a maara dị ka "eko achịcha green". PROTOGA nwetara teknụzụ na-edezi mkpụrụ ndụ ihe nketa microalgae dị elu yana teknụzụ fermentation microalgae dị ala. N'otu oge ahụ, PROTOGA na-emepụta teknụzụ fotoautotrophic . Ozugbo nkà na ụzụ ozuzu na-eto eto ma nwee ike itinye ya n'ọrụ n'ọtụtụ-mmepụta, ọ ga-ebuli mmepụta arụmọrụ na-agbanwe CO2 na ngwaahịa ndị dabeere na bio.