Discovery ntawm Microalgae Extracellular Vesicles

Extracellular vesicles yog endogenous nano-size vesicles secreted los ntawm cov hlwb, xws li ntawm 30-200 nm nyob rau hauv txoj kab uas hla enveloped nyob rau hauv ib tug lipid bilayer membrane, uas muaj nucleic acids, proteins, lipids thiab metabolites, thiab lwm yam. uas muaj kev koom tes hauv kev sib pauv khoom ntawm cov hlwb.Extracellular vesicles tuaj yeem zais los ntawm ntau lub hlwb nyob rau hauv ib txwm muaj thiab pathological mob, uas feem ntau yog los ntawm cov polyvesicles tsim los ntawm intracellular lysosomal hais thiab raug tso tawm mus rau hauv lub extracellular matrix tom qab fusion ntawm extracellular membrane thiab cell membrane ntawm lub polyvesicles.Vim nws cov immunogenicity tsawg, tsis muaj tshuaj lom neeg phiv, lub hom phiaj muaj zog, muaj peev xwm hla cov ntshav-hlwb barrier thiab lwm yam ntxwv, nws tau raug suav hais tias yog cov muaj peev xwm nqa tshuaj.Xyoo 2013, Nobel Prize hauv Physiology thiab Tshuaj tau muab tsub rau peb tus kws tshawb fawb txog kev tshawb fawb ntawm cov hlab ntsha sab nraud.Txij thaum ntawd los, lub voj voog kev kawm thiab kev lag luam tau teeb tsa kev nce qib ntawm kev tshawb fawb thiab kev tsim kho, kev siv thiab kev lag luam.

Extracellular vesicles los ntawm cov nroj tsuag hlwb yog nplua nuj nyob rau hauv tshwj xeeb active Cheebtsam, me me thiab muaj peev xwm nyob rau hauv cov ntaub so ntswg nkag.Feem ntau ntawm lawv tuaj yeem noj thiab ncaj qha absorbed rau hauv txoj hnyuv.Piv txwv li, ginseng vesicles yog qhov tsim nyog rau kev sib txawv ntawm cov qia hlwb rau hauv cov hlab ntsha hlwb, thiab cov ginger vesicles tuaj yeem tswj cov plab hnyuv thiab txo cov kab mob colitis.Microalgae yog cov nroj tsuag qub tshaj plaws hauv lub ntiaj teb.Muaj ze li ntawm 300,000 hom microalgae dav dav hauv dej hiav txwv, pas dej, dej ntws, suab puam, toj siab, glaciers thiab lwm qhov chaw, nrog rau cov yam ntxwv hauv cheeb tsam.Thaum lub sij hawm evolution ntawm 3 billion lub ntiaj teb, microalgae yeej ib txwm muaj peev xwm vam meej raws li ib lub hlwb nyob rau hauv lub ntiaj teb, uas yog inseparable ntawm lawv extraordinary loj hlob thiab kho tus kheej muaj peev xwm.

Microalgal extracellular vesicles yog cov khoom siv biomedical tshiab nrog kev nyab xeeb dua thiab ruaj khov.Microalgae muaj ntau yam zoo hauv kev tsim cov vesicles extracellular, xws li cov txheej txheem kab lis kev cai yooj yim, tswj tau, pheej yig, kev loj hlob sai, siab tso tawm ntawm cov vesicles thiab yooj yim rau kev tsim kho.Hauv kev tshawb fawb yav dhau los, microalgal extracellular vesicles tau pom tias yooj yim nyob hauv cov hlwb.Hauv cov qauv tsiaj, lawv tau pom tias tau nqus ncaj qha los ntawm lub plab thiab enriched hauv cov ntaub so ntswg.Tom qab nkag mus rau cytoplasm, nws tuaj yeem kav ntev li ob peb hnub, uas yog qhov tsim nyog rau kev tso tshuaj mus ntev.

Tsis tas li ntawd, microalgal extracellular vesicles yuav tsum thauj ntau yam tshuaj, uas txhim kho kev ruaj ntseg ntawm cov molecules, qeeb tso tawm, qhov ncauj adaptability, thiab lwm yam, daws cov kev tswj hwm cov tshuaj uas twb muaj lawm.Yog li ntawd, txoj kev loj hlob ntawm microalgae extracellular vesicles muaj qhov ua tau zoo hauv kev hloov kho thiab kev lag luam.