Astaxanthin Synthesis hauv Chlamydomonas Reinhardtii

PROTOGA tsis ntev los no tau tshaj tawm tias nws tau ua tiav cov khoom siv ntuj tsim astaxanthin hauv Chlamydomonas Reinhardtii los ntawm Microalgae Genetic Modification Platform, thiab tam sim no tab tom tsim cov cuab yeej kev txawj ntse thiab kev tshawb fawb hauv qab. Nws tau tshaj tawm tias qhov no yog qhov thib ob tiam ntawm engineering hlwb nteg tawm hauv astaxanthin pipeline thiab yuav txuas ntxiv mus. Thawj tiam ntawm engineering hlwb tau nkag mus rau theem kev sim ntsuas. Lub synthesis ntawm astaxanthin nyob rau hauv Chlamydomonas Reinhardtii rau industrial ntau lawm yuav zoo dua nyob rau hauv tus nqi, productivity thiab zoo tshaj cov Haematococcus Pluvialis.

Astaxanthin yog lub ntuj thiab hluavtaws xanthophyll thiab nonprovitamin A carotenoid, muaj peev xwm antioxidant, tiv thaiv inflammatory thiab antineoplastic kev ua ub no. Nws cov tshuaj tiv thaiv antioxidant yog 6000 npaug ntawm cov vitamin C thiab 550 npaug ntawm cov vitamin E. Astaxanthin muaj kev ua tau zoo hauv kev tiv thaiv kab mob, kev saib xyuas cov kab mob plawv, lub qhov muag thiab lub hlwb kev noj qab haus huv, tawv nqaij muaj zog, tiv thaiv kev laus thiab lwm yam kev siv. Astaxanthin feem ntau siv rau hauv cov khoom kho mob, cov khoom noj khoom haus khoom noj khoom haus nrog cov txiaj ntsig kev noj qab haus huv thiab ntxiv rau hauv cov tshuaj pleev ib ce nrog cov nyhuv antioxidant.

Kev lag luam thoob ntiaj teb astaxanthin xav tias yuav ncav cuag $ 2.55 nphom los ntawm 2025 raws li Grand View Research. Tam sim no, cov haujlwm ntawm astaxanthin tau los ntawm cov tshuaj synthesis thiab Phaffia rhodozyma yog qis dua li ntawm ntuj levo-astaxanthin muab tau los ntawm microalgae vim nws cov yam ntxwv kho qhov muag. Txhua yam ntuj tsim levo-astaxanthin hauv khw los ntawm Haematococcus Pluvialis. Txawm li cas los xij, vim nws txoj kev loj hlob qeeb, lub voj voog kab lis kev cai ntev thiab yooj yim los cuam tshuam los ntawm ib puag ncig, kev tsim muaj peev xwm ntawm Haematococcus Pluvialis yog txwv.

Raws li lub hauv paus tshiab ntawm cov khoom ntuj tsim thiab chassis cell ntawm hluavtaws biology, microalgae muaj complex metabolic network thiab biosynthesis zoo. Chlamydomonas Reinhardtii yog tus qauv chassis, hu ua "ntsuab poov xab". PROTOGA mastered lub advanced microalgae genetic editing technology thiab downstream microalgae fermentation technology. Nyob rau tib lub sijhawm, PROTOGA tab tom tsim cov thev naus laus zis photoautotrophic .Thaum yug me nyuam cov cuab yeej ua kom paub tab thiab tuaj yeem siv rau ntawm kev tsim cov nplai, nws yuav txhawb nqa cov khoom siv hluav taws xob hloov pauv CO2 rau cov khoom siv bio-based.