ʻIke ʻia o nā Microalgae Extracellular Vesicles

ʻO nā vesicles extracellular nā endogenous nano-size vesicles i hūnā ʻia e nā cell, mai ka 30-200 nm i ke anawaena i hoʻopuni ʻia i loko o kahi membrane bilayer lipid, e lawe ana i nā waikawa nucleic, nā protein, nā lipids a me nā metabolites, etc. nā mea i komo i ka hoʻololi ʻana i nā mea ma waena o nā cell. Hiki ke hūnā ʻia nā vesicles extracellular e nā ʻano mea like ʻole ma lalo o nā kūlana maʻamau a me nā pathological, ka mea nui mai nā polyvesicles i hana ʻia e nā ʻāpana lysosomal intracellular a hoʻokuʻu ʻia i loko o ka matrix extracellular ma hope o ka hui ʻana o ka membrane extracellular a me ka membrane cell o nā polyvesicles. Ma muli o kāna immunogenicity haʻahaʻa, nā hopena ʻaoʻao ʻona ʻole, ka huli ikaika ʻana, ka hiki ke hele i ka pale koko-lolo a me nā ʻano ʻē aʻe, ua manaʻo ʻia ʻo ia ka mea lawe lāʻau. Ma 2013, ua hāʻawi ʻia ka Nobel Prize in Physiology and Medicine i ʻekolu mau ʻepekema e pili ana i ke aʻo ʻana i nā vesicle waho. Mai ia manawa, ua hoʻomaka ka poʻe hoʻonaʻauao a me nā ʻoihana i ka piʻi ʻana o ka noiʻi a me ka hoʻomohala ʻana o nā vesicle extracellular, noi a me ka hoʻolaha ʻana.

Loaʻa nā vesicle extracellular mai nā mea kanu i nā mea hana kūʻokoʻa, liʻiliʻi i ka nui a hiki ke komo i ke kino. Hiki ke lawe ʻia ka hapa nui o lākou a komo pololei i loko o ka ʻōpū. ʻO kahi laʻana, hiki i nā vesicles ginseng ke hoʻokaʻawale i nā cell stem i loko o nā pūnana nerve, a hiki i nā vesicle ginger ke hoʻoponopono i nā pua ʻōpū a hoʻēmi i ka colitis. ʻO Microalgae nā mea kanu kahiko loa ma ka Honua. Aia ma kahi o 300,000 mau ʻano microalgae i laha nui ʻia ma nā moana, nā loko, nā muliwai, nā wao nahele, nā pāpū, nā glaciers a me nā wahi ʻē aʻe, me nā ʻano ʻāpana kūʻokoʻa. I ka wā o ka ulu ʻana o ka Honua 3 biliona, ua hiki i nā microalgae ke holomua ma ke ʻano he hoʻokahi cell ma ka Honua, ʻaʻole hiki ke hoʻokaʻawale ʻia mai ko lākou ulu ʻana a me ka hiki ke hoʻoponopono iā ia iho.

ʻO nā vesicles extracellular microalgal nā mea hana biomedical hou me ka palekana kiʻekiʻe a me ke kūpaʻa. He nui nā pōmaikaʻi o ka Microalgae i ka hana ʻana i nā vesicle extracellular, e like me ke kaʻina moʻomeheu maʻalahi, hiki ke hoʻopaʻa ʻia, ʻoi aku ka maikaʻi, ulu wikiwiki, kiʻekiʻe o nā vesicles a maʻalahi hoʻi e ʻenekinia. I nā haʻawina mua, ua ʻike ʻia nā microalgal extracellular vesicles e maʻalahi i loko o nā cell. I loko o nā hiʻohiʻona holoholona, ​​ua ʻike ʻia lākou e komo pono ʻia i loko o ka ʻōpū a hoʻonui ʻia i nā kiko kikoʻī. Ma hope o ke komo ʻana i ka cytoplasm, hiki iā ia ke hoʻomau no kekahi mau lā, kahi kūpono i ka hoʻokuʻu ʻana i ka lāʻau lapaʻau lōʻihi.

Eia kekahi, manaʻo ʻia nā microalgal extracellular vesicles e hoʻouka i nā ʻano lāʻau like ʻole, e hoʻomaikaʻi ai i ke kūpaʻa o nā molekala, hoʻokuʻu lohi, adaptability oral, etc. No laila, ʻo ka hoʻomohala ʻana o nā microalgae extracellular vesicle he kiʻekiʻe kūpono i ka hoʻololi ʻana i ke kino a me ka ʻoihana.