Gano Microalgae Extracellular Vesicles

Extracellular vesicles ne endogenous Nano-size vesicles secreted by Kwayoyin, jere daga 30-200 nm a diamita lullube a cikin wani lipid bilayer membrane, wanda dauke da nucleic acid, sunadarai, lipids da metabolites, da dai sauransu Extracellular vesicles ne babban kayan aikin intercellular sadarwa, wanda ke da hannu wajen musayar kayan aiki tsakanin sel. Za a iya ɓoye ɓoyayyiyar ƙwayoyin cuta ta sel daban-daban a ƙarƙashin yanayin al'ada da cututtukan cututtuka, waɗanda galibi sun fito ne daga polyvesicles da aka kafa ta ƙwayoyin lysosomal na intracellular kuma ana fitar da su a cikin matrix na waje bayan haɗuwa da membrane na extracellular da membrane cell na polyvesicles. Saboda ƙarancin immunogenicity ɗin sa, illolin da ba mai guba ba, ƙaƙƙarfan manufa, ƙarfin ketare shingen kwakwalwar jini da sauran halaye, an ɗauke shi azaman mai ɗaukar magunguna. A cikin 2013, an ba da lambar yabo ta Nobel a fannin ilimin halittar jiki da likitanci ga masana kimiyya uku masu alaƙa da nazarin vesicles na waje. Tun daga wannan lokacin, da'irar ilimi da masana'antu sun tashi sama da haɓaka bincike da haɓaka vesicles na waje, aikace-aikace da kasuwanci.

Extracellular vesicles daga sel shuka suna da wadata a cikin abubuwan da ke aiki na musamman, ƙanana kuma suna iya shiga cikin nama. Yawancin su ana iya ɗaukar su kai tsaye a shiga cikin hanji. Alal misali, ginseng vesicles suna taimakawa wajen bambance bambance-bambancen kwayoyin halitta zuwa sel jijiya, kuma ginger vesicles na iya daidaita flora na hanji da rage colitis. Microalgae sune tsire-tsire masu kwayar halitta mafi tsufa a duniya. Akwai kusan nau'ikan microalgae kusan 300,000 da aka rarraba a cikin tekuna, tafkuna, koguna, hamada, faranti, glaciers da sauran wurare, waɗanda ke da halaye na musamman na yanki. A lokacin juyin halitta na duniya biliyan 3, microalgae koyaushe suna iya bunƙasa a matsayin sel guda ɗaya a duniya, waɗanda ba za su iya rabuwa da girma na ban mamaki da ikon gyara kansu ba.

Microalgal extracellular vesicles sabbin kayan aikin likitanci ne tare da aminci da kwanciyar hankali. Microalgae suna da fa'idodi da yawa a cikin samar da vesicles na waje, kamar tsarin al'adu mai sauƙi, mai sarrafawa, arha, haɓaka mai sauri, babban fitarwa na vesicles da sauƙin yin injiniya. A cikin binciken da suka gabata, an gano ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin cuta waɗanda ke cikin sauƙi cikin sauƙi ta sel. A cikin nau'ikan dabbobi, an gano su kai tsaye a cikin hanji kuma an wadatar da su a cikin takamaiman kyallen takarda. Bayan shigar da cytoplasm, zai iya wucewa na kwanaki da yawa, wanda ke da tasiri ga sakin magani na dogon lokaci.

Bugu da kari, ana sa ran microalgal extracellular vesicles za su loda magunguna iri-iri, wadanda ke inganta zaman lafiyar kwayoyin halitta, jinkirin sakin jiki, daidaitawar baki, da dai sauransu, warware matsalolin da ke tattare da sarrafa magunguna. Saboda haka, ci gaban microalgae extracellular vesicles yana da babban yuwuwar a cikin canjin asibiti da masana'antu.