Extracellular vesicles ne endogenous nano vesicles boye ta sel, da diamita na 30-200 nm, nannade a cikin wani lipid bilayer membrane, dauke da nucleic acid, sunadarai, lipids, da metabolites. Extracellular vesicles shine babban kayan aiki don sadarwar intercellular kuma suna shiga cikin musayar abubuwa tsakanin sel. Extracellular vesicles za a iya boye ta daban-daban Kwayoyin a karkashin al'ada da pathological yanayi, yafi samu daga samuwar multivesicular lysosomal barbashi a cikin sel. Bayan hadewar membrane na waje da membrane na waje na sel masu yawa, an sake su cikin matrix extracellular. Saboda ƙarancin immunogenicity ɗin sa, illolin marasa guba, ƙarfin niyya mai ƙarfi, da ikon ketare shingen jini-kwakwalwa, ana ɗaukarsa mai yuwuwar jigilar magunguna. A cikin 2013, an ba da lambar yabo ta Nobel a fannin ilimin halittar jiki ko kuma likitanci ga masana kimiyya uku da ke da hannu a cikin nazarin vesicles na waje. Tun daga wannan lokacin, an sami ɗimbin bincike, aikace-aikace, da tallace-tallace na vesicles na waje a cikin ilimi da masana'antu.

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Extracellular vesicles daga sel tsire-tsire suna da wadata a cikin sinadarai masu aiki na musamman, suna da ƙaramin ƙara, kuma suna iya shiga cikin kyallen takarda. Yawancinsu ana iya cinye su kai tsaye a shiga cikin hanji. Misali, kumfa ginseng suna da amfani ga bambance-bambancen kwayar halitta a cikin sel jijiya, yayin da ginger kumfa zai iya daidaita microbiota na gut kuma yana rage colitis. Microalgae sune mafi dadewa tsire-tsire masu kwayar halitta guda daya a Duniya. Akwai kusan nau'ikan microalgae kusan 300000, waɗanda aka rarraba a cikin tekuna, tafkuna, koguna, hamada, faranti, glaciers da sauran wurare, tare da halayen yanki na musamman. A cikin juyin halittar duniya biliyan 3, microalgae koyaushe suna iya bunƙasa a matsayin sel guda ɗaya a Duniya, waɗanda ke da alaƙa da haɓakar su na ban mamaki da iyawar warkarwa.

 

Microalgae extracellular vesicles wani sabon abu ne mai aiki na biomedical tare da babban aminci da kwanciyar hankali. Microalgae suna da fa'idodin tsarin noma mai sauƙi da sarrafawa, ƙarancin farashi, saurin girma, yawan amfanin ƙasa, da injiniya mai sauƙi a cikin samar da vesicles na waje. A cikin binciken da aka yi a baya, an gano cewa ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin cuta suna cikin sauƙi. A cikin nau'ikan dabbobi, an gano cewa an shafe su kai tsaye ta cikin hanji kuma an wadatar da su a cikin takamaiman kyallen takarda. Bayan shigar da cytoplasm, zai iya wucewa na kwanaki da yawa, wanda ke da amfani ga ci gaba da sakin kwayoyi na dogon lokaci.

 

Bugu da kari, microalgae extracellular vesicles suna da yuwuwar lodin magunguna da yawa, haɓaka kwanciyar hankali na ƙwayoyin cuta, ci gaba da sakin jiki, daidaitawar baka, da warware matsalolin isar da magunguna da ake dasu. Saboda haka, ci gaban microalgae extracellular vesicles yana da babban yuwuwar a cikin fassarar asibiti da masana'antu.


Lokacin aikawa: Yuli-29-2024